Promoting the Quality of Medicines Plus (PQM+)

Guidance and job aids for manufacturing quality-assured gentamicin

An antibiotic usually marketed as an injectable solution or topical ointment, gentamicin is used to treat serious bacterial infections, including childhood pneumonia.

This report analyzes the physicochemical, biopharmaceutics, and toxicological properties of gentamicin and provides information on formulation, efficacy, adverse effects, manufacturing, and more. The report includes guidance for manufacturers and other stakeholders to improve access and supply of priority essential medicines.

Accompanying the report are two job aids that offer quick, easy-to-follow instructions to assist staff in conducting laboratory tests and preparing dossiers for gentamicin.